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Structure paper

TitleCrystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling.
Journal, issue, pagesScience, Vol. 358, Page 377-381, Year 2017
Publish dateSep 14, 2017 (structure data deposition date)
Authorsde Araujo, M.E.G. / Naschberger, A. / Furnrohr, B.G. / Stasyk, T. / Dunzendorfer-Matt, T. / Lechner, S. / Welti, S. / Kremser, L. / Shivalingaiah, G. / Offterdinger, M. ...de Araujo, M.E.G. / Naschberger, A. / Furnrohr, B.G. / Stasyk, T. / Dunzendorfer-Matt, T. / Lechner, S. / Welti, S. / Kremser, L. / Shivalingaiah, G. / Offterdinger, M. / Lindner, H.H. / Huber, L.A. / Scheffzek, K.
External linksScience / PubMed:28935770
MethodsX-ray diffraction
Resolution2.3 - 2.898 Å
Structure data

PDB-6ehp:
The crystal structure of the human LAMTOR complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6ehr:
The crystal structure of the human LAMTOR-RagA CTD-RagC CTD complex
Method: X-RAY DIFFRACTION / Resolution: 2.898 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Scaffolding complex / Rag-GTPase / mTOR / Ragulator / mTORC1 / Rag-GTPases

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