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Structure paper

TitleEpigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 139, Page 14436-14442, Year 2017
Publish dateJun 13, 2017 (structure data deposition date)
AuthorsWang, W. / Xu, L. / Hu, L. / Chong, J. / He, C. / Wang, D.
External linksJ. Am. Chem. Soc. / PubMed:28933854
MethodsX-ray diffraction
Resolution3.404 - 3.6 Å
Structure data

PDB-5w4u:
Pol II elongation complex with an N6-methyladenine-containing template
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

PDB-5w51:
Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP
Method: X-RAY DIFFRACTION / Resolution: 3.404 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-2KH:
5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsDNA BINDING PROTEIN/RNA/DNA / Complex / DNA BINDING PROTEIN / DNA BINDING PROTEIN-RNA-DNA complex

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