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TitleNeutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine-Nanobody Complex.
Journal, issue, pagesFront Immunol, Vol. 8, Page 884-884, Year 2017
Publish dateAug 27, 2012 (structure data deposition date)
AuthorsDesmyter, A. / Spinelli, S. / Boutton, C. / Saunders, M. / Blachetot, C. / de Haard, H. / Denecker, G. / Van Roy, M. / Cambillau, C. / Rommelaere, H.
External linksFront Immunol / PubMed:28871249
MethodsX-ray diffraction
Resolution2.55 Å
Structure data

PDB-4grw:
Structure of a complex of human IL-23 with 3 Nanobodies (Llama vHHs)
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • lama glama (llama)
KeywordsIMMUNE SYSTEM / Cytokine / immunoglobulin fold / VHH domain

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