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Structure paper

TitlePolycomb-like proteins link the PRC2 complex to CpG islands
Journal, issue, pagesNature, Vol. 549, Page 287-291, Year 2017
Publish dateApr 11, 2017 (structure data deposition date)
AuthorsLi, H. / Liefke, R. / Jiang, J. / Kurland, J.V. / Tian, W. / Deng, P. / Zhang, W. / He, Q. / Patel, D.J. / Bulyk, M.L. ...Li, H. / Liefke, R. / Jiang, J. / Kurland, J.V. / Tian, W. / Deng, P. / Zhang, W. / He, Q. / Patel, D.J. / Bulyk, M.L. / Shi, Y. / Wang, Z.
External linksNature / PubMed:28869966
MethodsX-ray diffraction
Resolution1.9 - 2.4 Å
Structure data

PDB-5xfn:
Structure of the N-terminal domains of PHF1
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5xfo:
Structure of the N-terminal domains of PHF1
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5xfp:
Binary complex of PHF1 and a double stranded DNA
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5xfq:
Ternary complex of PHF1, a DNA duplex and a histone peptide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-5xfr:
Ternary complex of MTF2, DNA and histone
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

Source
  • homo sapiens (human)
  • synthetic construct (others)
  • mus musculus (house mouse)
KeywordsTRANSCRIPTION / PHF1 / PCL1 / PRC2 / TRANSCRIPTION/DNA / DNA / TRANSCRIPTION-DNA complex / histone / MTF2 / PCL2

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