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TitleImproving the thermal stability of cellobiohydrolase Cel7A from Hypocrea jecorina by directed evolution.
Journal, issue, pagesJ. Biol. Chem., Vol. 292, Page 17418-17430, Year 2017
Publish dateJun 20, 2017 (structure data deposition date)
AuthorsGoedegebuur, F. / Dankmeyer, L. / Gualfetti, P. / Karkehabadi, S. / Hansson, H. / Jana, S. / Huynh, V. / Kelemen, B.R. / Kruithof, P. / Larenas, E.A. ...Goedegebuur, F. / Dankmeyer, L. / Gualfetti, P. / Karkehabadi, S. / Hansson, H. / Jana, S. / Huynh, V. / Kelemen, B.R. / Kruithof, P. / Larenas, E.A. / Teunissen, P.J.M. / Stahlberg, J. / Payne, C.M. / Mitchinson, C. / Sandgren, M.
External linksJ. Biol. Chem. / PubMed:28860192
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-5oa5:
CELLOBIOHYDROLASE I (CEL7A) FROM HYPOCREA JECORINA WITH IMPROVED THERMAL STABILITY
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • hypocrea jecorina (fungus)
KeywordsHYDROLASE / CELLULASE / PROTEIN ENGINEERING

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