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Structure paper

TitleStructures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page E7564-E7573, Year 2017
Publish dateJul 19, 2017 (structure data deposition date)
AuthorsWu, Y. / Zhu, Y.H. / Gao, F. / Jiao, Y.J. / Oladejo, B.O. / Chai, Y. / Bi, Y.H. / Lu, S. / Dong, M.Q. / Zhang, C. ...Wu, Y. / Zhu, Y.H. / Gao, F. / Jiao, Y.J. / Oladejo, B.O. / Chai, Y. / Bi, Y.H. / Lu, S. / Dong, M.Q. / Zhang, C. / Huang, G.M. / Wong, G. / Li, N. / Zhang, Y.F. / Li, Y. / Feng, W.H. / Shi, Y. / Liang, M.F. / Zhang, R.G. / Qi, J.X. / Gao, G.F.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28827346
MethodsX-ray diffraction
Resolution2.1 - 3.398 Å
Structure data

PDB-5y0w:
The structure of RVFV Gn head domain
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-5y0y:
RVFV GN-AU
Method: X-RAY DIFFRACTION / Resolution: 3.398 Å

PDB-5y10:
SFTSV Gn head domain
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-5y11:
SFTSV GN with neutralizing antibody MAb4-5
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-AU:
Unknown entry

Source
  • rift valley fever virus
  • severe fever with thrombocytopenia virus
  • homo sapiens (human)
KeywordsVIRAL PROTEIN / RVFV / Glycoprotein N (Gn) / bunyavirus / phlebovirus / GN / SFTSV / IMMUNE SYSTEM/VIRAL SYSTEM / NEUTRALIZING ANTIBODY / IMMUNE SYSTEM-VIRAL SYSTEM complex

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