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Structure paper

TitleA novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Journal, issue, pagesElife, Vol. 6, Year 2017
Publish dateApr 21, 2017 (structure data deposition date)
AuthorsSdano, M.A. / Fulcher, J.M. / Palani, S. / Chandrasekharan, M.B. / Parnell, T.J. / Whitby, F.G. / Formosa, T. / Hill, C.P.
External linksElife / PubMed:28826505
MethodsX-ray diffraction
Resolution1.8 - 2.198 Å
Structure data

PDB-5vkl:
SPT6 tSH2-RPB1 1476-1500 pS1493
Method: X-RAY DIFFRACTION / Resolution: 2.198 Å

PDB-5vko:
SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
KeywordsTRANSCRIPTION / SH2 domain phosphoserine histone chaperone transcription / SH2 domain phosphorylation histone chaperone transcription

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