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TitlePreferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans.
Journal, issue, pagesSci Immunol, Vol. 2, Year 2017
Publish dateNov 18, 2016 (structure data deposition date)
AuthorsAndrews, S.F. / Joyce, M.G. / Chambers, M.J. / Gillespie, R.A. / Kanekiyo, M. / Leung, K. / Yang, E.S. / Tsybovsky, Y. / Wheatley, A.K. / Crank, M.C. ...Andrews, S.F. / Joyce, M.G. / Chambers, M.J. / Gillespie, R.A. / Kanekiyo, M. / Leung, K. / Yang, E.S. / Tsybovsky, Y. / Wheatley, A.K. / Crank, M.C. / Boyington, J.C. / Prabhakaran, M.S. / Narpala, S.R. / Chen, X. / Bailer, R.T. / Chen, G. / Coates, E. / Kwong, P.D. / Koup, R.A. / Mascola, J.R. / Graham, B.S. / Ledgerwood, J.E. / McDermott, A.B.
External linksSci Immunol / PubMed:28783708
MethodsX-ray diffraction
Resolution1.361 - 2.461 Å
Structure data

PDB-5ty6:
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 13-1b02 Fab.
Method: X-RAY DIFFRACTION / Resolution: 1.361 Å

PDB-5u4r:
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 53-1A09 Fab.
Method: X-RAY DIFFRACTION / Resolution: 1.762 Å

PDB-5wca:
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 27-1C08 Fab.
Method: X-RAY DIFFRACTION / Resolution: 1.369 Å

PDB-5wcc:
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 02-1F07 Fab.
Method: X-RAY DIFFRACTION / Resolution: 2.461 Å

PDB-5wcd:
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 04-1D02 Fab.
Method: X-RAY DIFFRACTION / Resolution: 1.814 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-15P:
POLYETHYLENE GLYCOL (N=34) / precipitant*YM

ChemComp-PO4:
PHOSPHATE ION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antibody / influenza / human vaccine trial

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