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TitleMolecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Journal, issue, pagesSci Rep, Vol. 7, Page 5532-5532, Year 2017
Publish dateMar 3, 2017 (structure data deposition date)
AuthorsLee, H.T. / Lee, J.Y. / Lim, H. / Lee, S.H. / Moon, Y.J. / Pyo, H.J. / Ryu, S.E. / Shin, W. / Heo, Y.S.
External linksSci Rep / PubMed:28717238
MethodsX-ray diffraction
Resolution2.661 - 3.1 Å
Structure data

PDB-5x8l:
PD-L1 in complex with atezolizumab
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-5x8m:
PD-L1 in complex with durvalumab
Method: X-RAY DIFFRACTION / Resolution: 2.661 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / complex / antibody

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