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Structure paper

TitleDramatic and concerted conformational changes enable rhodocetin to block alpha 2 beta 1 integrin selectively.
Journal, issue, pagesPLoS Biol., Vol. 15, Page e2001492-e2001492, Year 2017
Publish dateSep 30, 2016 (structure data deposition date)
AuthorsEble, J.A. / McDougall, M. / Orriss, G.L. / Niland, S. / Johanningmeier, B. / Pohlentz, G. / Meier, M. / Karrasch, S. / Estevao-Costa, M.I. / Martins Lima, A. / Stetefeld, J.
External linksPLoS Biol. / PubMed:28704364
MethodsX-ray diffraction
Resolution3.006 Å
Structure data

PDB-5thp:
Rhodocetin in complex with the integrin alpha2-A domain
Method: X-RAY DIFFRACTION / Resolution: 3.006 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • calloselasma rhodostoma (Malayan pit viper)
KeywordsCELL ADHESION / C-type lectin / integrin / venom / coagulation

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