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Structure paper

TitleZn(II) mediates vancomycin polymerization and potentiates its antibiotic activity against resistant bacteria.
Journal, issue, pagesSci Rep, Vol. 7, Page 4893-4893, Year 2017
Publish dateOct 13, 2016 (structure data deposition date)
AuthorsZarkan, A. / Macklyne, H.R. / Chirgadze, D.Y. / Bond, A.D. / Hesketh, A.R. / Hong, H.J.
External linksSci Rep / PubMed:28687742
MethodsX-ray diffraction
Resolution0.95 - 1 Å
Structure data

PDB-5m2h:
Crystal structure of vancomycin-Zn(II)-citrate complex
Method: X-RAY DIFFRACTION / Resolution: 0.95 Å

PDB-5m2k:
Crystal structure of vancomycin-Zn(II) complex
Method: X-RAY DIFFRACTION / Resolution: 1 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CIT:
CITRIC ACID

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • amycolatopsis orientalis (bacteria)
KeywordsANTIBIOTIC / Vancomycin / zinc / glycopeptide

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