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Structure paper

TitleStructural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 490, Page 1011-1017, Year 2017
Publish dateNov 29, 2016 (structure data deposition date)
AuthorsSorrentino, L. / Cossu, F. / Milani, M. / Aliverti, A. / Mastrangelo, E.
External linksBiochem. Biophys. Res. Commun. / PubMed:28666871
MethodsX-ray diffraction
Resolution3.1 - 3.5 Å
Structure data

PDB-5miu:
G307E variant of Murine Apoptosis Inducing Factor (oxidized state)
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-5miv:
G307E variant of murine Apoptosis Inducing Factor in complex with NAD+
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-HOH:
WATER

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

Source
  • mus musculus (house mouse)
KeywordsOXIDOREDUCTASE / Apoptosis Inducing Factor OXIDOREDUCTASE / Apoptosis Inducing Factor

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