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TitleGlycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7.
Journal, issue, pagesStructure, Vol. 25, Page 1100-1110.e5, Year 2017
Publish dateDec 29, 2016 (structure data deposition date)
AuthorsFulcher, Y.G. / Prior, S.H. / Masuko, S. / Li, L. / Pu, D. / Zhang, F. / Linhardt, R.J. / Van Doren, S.R.
External linksStructure / PubMed:28648610
MethodsNMR (solution)
Structure data

PDB-5ue2:
proMMP-7 with heparin octasaccharide bridging between domains
Method: SOLUTION NMR

PDB-5ue5:
proMMP-7 with heparin octasaccharide bound to the catalytic domain
Method: SOLUTION NMR

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHYDROLASE / glycan complex with protein / enzyme complex with heparin oligosaccharide / zymogen / allosteric effector site

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