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| Title | Catalytic-site design for inverse heavy-enzyme isotope effects in human purine nucleoside phosphorylase. |
|---|---|
| Journal, issue, pages | Proc. Natl. Acad. Sci. U.S.A., Vol. 114, Page 6456-6461, Year 2017 |
| Publish date | Jan 8, 2017 (structure data deposition date) |
Authors | Harijan, R.K. / Zoi, I. / Antoniou, D. / Schwartz, S.D. / Schramm, V.L. |
External links | Proc. Natl. Acad. Sci. U.S.A. / PubMed:28584087 |
| Methods | X-ray diffraction |
| Resolution | 2.2 Å |
| Structure data | ![]() PDB-5ugf: |
| Chemicals | ![]() ChemComp-PO4: ![]() ChemComp-IM5: ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / phosphorylase / inhibitor / transition state analogue / purine salvage pathway / TRANSFERASE-TRANSFERASE INHIBITOR complex |
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homo sapiens (human)
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