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Structure paper

TitleCrystal structures of human Fabs targeting the Bexsero meningococcal vaccine antigen NHBA.
Journal, issue, pagesActa Crystallogr F Struct Biol Commun, Vol. 73, Page 305-314, Year 2017
Publish dateFeb 10, 2017 (structure data deposition date)
AuthorsMaritan, M. / Cozzi, R. / Lo Surdo, P. / Veggi, D. / Bottomley, M.J. / Malito, E.
External linksActa Crystallogr F Struct Biol Commun / PubMed:28580917
MethodsX-ray diffraction
Resolution1.503 - 2.75 Å
Structure data

PDB-5n4g:
human Fab fragment 12E1 against NHBA from Neisseria meningitidis
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-5n4j:
human Fab fragment 10C3 against NHBA from Neisseria meningitidis
Method: X-RAY DIFFRACTION / Resolution: 1.503 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fab fragment / antibody / human

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