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Structure paper

TitleStructural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
Journal, issue, pagesEMBO J., Vol. 36, Page 2204-2215, Year 2017
Publish dateJan 17, 2017 (structure data deposition date)
AuthorsSuckling, R.J. / Korona, B. / Whiteman, P. / Chillakuri, C. / Holt, L. / Handford, P.A. / Lea, S.M.
External linksEMBO J. / PubMed:28572448
MethodsX-ray diffraction
Resolution1.86 - 2.8 Å
Structure data

PDB-5mvx:
Human DLL4 C2-EGF3
Method: X-RAY DIFFRACTION / Resolution: 2.17 Å

PDB-5mw5:
Human Jagged2 C2-EGF2
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-5mw7:
Human Jagged2 C2-EGF3
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5mwb:
Human Notch-2 EGF11-13
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

PDB-5mwf:
Human Jagged2 C2-EGF2
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-FUC:
alpha-L-fucopyranose

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CA:
Unknown entry

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / C2 / EGF / Notch / signaling / receptor

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