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TitleA disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding.
Journal, issue, pagesSci Signal, Vol. 10, Year 2017
Publish dateJan 6, 2015 (structure data deposition date)
AuthorsZuo, J. / Willcox, C.R. / Mohammed, F. / Davey, M. / Hunter, S. / Khan, K. / Antoun, A. / Katakia, P. / Croudace, J. / Inman, C. ...Zuo, J. / Willcox, C.R. / Mohammed, F. / Davey, M. / Hunter, S. / Khan, K. / Antoun, A. / Katakia, P. / Croudace, J. / Inman, C. / Parry, H. / Briggs, D. / Malladi, R. / Willcox, B.E. / Moss, P.
External linksSci Signal / PubMed:28559451
MethodsX-ray diffraction
Resolution2.35 Å
Structure data

PDB-4s0u:
Crystal structure of NKG2D in complex with ULBP6
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Leukaemia / Graft versus Leukaemia / c-type lectin domain / NKG2D / NKG2DL / affinity and autoimmunity

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