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Title | Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. |
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Journal, issue, pages | Structure, Vol. 25, Page 878-889.e5, Year 2017 |
Publish date | Apr 22, 2016 (structure data deposition date) |
Authors | Lobner, E. / Humm, A.S. / Goritzer, K. / Mlynek, G. / Puchinger, M.G. / Hasenhindl, C. / Ruker, F. / Traxlmayr, M.W. / Djinovic-Carugo, K. / Obinger, C. |
External links | Structure / PubMed:28528777 |
Methods | X-ray diffraction |
Resolution | 1.663 - 4.3 Å |
Structure data | PDB-5jih: PDB-5jii: PDB-5jik: PDB-5k33: PDB-5kwg: |
Chemicals | ChemComp-HOH: ChemComp-PO4: ChemComp-GOL: ChemComp-NAG: |
Source |
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Keywords | IMMUNE SYSTEM / antibody engineering / immunoglobulin G1 / Fc fragment / glycosylations / CH3 domain / Fcab / HER2 / erbB-2 / antibody / human epidermal growth factor receptor 2 / HER2/neu / cell surface receptor |