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Structure paper

TitleClostridium difficile toxin glucosyltransferase domains in complex with a non-hydrolyzable UDP-glucose analogue.
Journal, issue, pagesJ. Struct. Biol., Vol. 198, Page 203-209, Year 2017
Publish dateFeb 8, 2017 (structure data deposition date)
AuthorsAlvin, J.W. / Lacy, D.B.
External linksJ. Struct. Biol. / PubMed:28433497
MethodsX-ray diffraction
Resolution1.851 - 2.75 Å
Structure data

PDB-5uqk:
Clostridium difficile toxin A (TcdA) glucosyltransferase domain in complex with U2F
Method: X-RAY DIFFRACTION / Resolution: 1.851 Å

PDB-5uql:
Clostridium difficile toxin A (TcdA) glucosyltransferase domain in complex with U2F
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

PDB-5uqm:
Clostridium difficile Toxin B (TcdB) glucosyltransferase domain in complex with U2F
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

PDB-5uqn:
Clostridium difficile Toxin B (TcdB) glucosyltransferase domain in complex with U2F
Method: X-RAY DIFFRACTION / Resolution: 2.06 Å

PDB-5uqt:
Clostridium difficile Toxin B (TcdB) glucosyltransferase domain co-crystallized with apigenin
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-U2F:
URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-AGI:
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

Source
  • clostridioides difficile (bacteria)
KeywordsTRANSFERASE / glucosyltransferase / toxin / HYDROLASE

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