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Structure paper

TitleParkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 24, Page 475-483, Year 2017
Publish dateFeb 8, 2017 (structure data deposition date)
AuthorsKumar, A. / Chaugule, V.K. / Condos, T.E.C. / Barber, K.R. / Johnson, C. / Toth, R. / Sundaramoorthy, R. / Knebel, A. / Shaw, G.S. / Walden, H.
External linksNat. Struct. Mol. Biol. / PubMed:28414322
MethodsX-ray diffraction
Resolution2.6 - 2.68 Å
Structure data

PDB-5n2w:
WT-Parkin and pUB complex
Method: X-RAY DIFFRACTION / Resolution: 2.68 Å

PDB-5n38:
S65DParkin and pUB complex
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-TMO:
trimethylamine oxide

ChemComp-HOH:
WATER

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
KeywordsLIGASE / Complex structure of Parkin and pUB / Transferase / S65DParkin pUB complex / splicing

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