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-Structure paper
Title | The structural basis for the functional comparability of factor VIII and the long-acting variant recombinant factor VIII Fc fusion protein. |
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Journal, issue, pages | J. Thromb. Haemost., Vol. 15, Page 1167-1179, Year 2017 |
Publish date | May 29, 2016 (structure data deposition date) |
![]() | Leksa, N.C. / Chiu, P.L. / Bou-Assaf, G.M. / Quan, C. / Liu, Z. / Goodman, A.B. / Chambers, M.G. / Tsutakawa, S.E. / Hammel, M. / Peters, R.T. ...Leksa, N.C. / Chiu, P.L. / Bou-Assaf, G.M. / Quan, C. / Liu, Z. / Goodman, A.B. / Chambers, M.G. / Tsutakawa, S.E. / Hammel, M. / Peters, R.T. / Walz, T. / Kulman, J.D. |
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Methods | X-ray diffraction |
Resolution | 4.19 Å |
Structure data | ![]() PDB-5k8d: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-CU: |
Source |
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![]() | BLOOD CLOTTING / Coagulation Factor / Factor VIII / human IgG1 Fc domain / Hemophilia A |