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Structure paper

TitleStructures of closed and open states of a voltage-gated sodium channel.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page E3051-E3060, Year 2017
Publish dateMar 28, 2017 (structure data deposition date)
AuthorsLenaeus, M.J. / Gamal El-Din, T.M. / Ing, C. / Ramanadane, K. / Pomes, R. / Zheng, N. / Catterall, W.A.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28348242
MethodsX-ray diffraction
Resolution2.85 - 3.2 Å
Structure data

PDB-5vb2:
Crystal structure of the NavAb voltage-gated sodium channel in a closed conformation
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-5vb8:
Crystal structure of the NavAb voltage-gated sodium channel in an open state
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-CPS:
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE / detergent*YM

ChemComp-PX4:
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE / DMPC, phospholipid*YM

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • arcobacter butzleri (bacteria)
KeywordsTRANSPORT PROTEIN / voltage-gated sodium channel

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