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TitleStructure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page E3243-E3250, Year 2017
Publish dateFeb 27, 2017 (structure data deposition date)
AuthorsKruusvee, V. / Lyst, M.J. / Taylor, C. / Tarnauskaite, Z. / Bird, A.P. / Cook, A.G.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28348241
MethodsX-ray diffraction
Resolution2.493 Å
Structure data

PDB-5naf:
Co-crystal structure of an MeCP2 peptide with TBLR1 WD40 domain
Method: X-RAY DIFFRACTION / Resolution: 2.493 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSCRIPTION / WD40 domain ; protein-peptide complex; transcriptional repressor; Rett syndrome

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