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TitleDomain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression.
Journal, issue, pagesNat Commun, Vol. 8, Page 14892-14892, Year 2017
Publish dateNov 28, 2016 (structure data deposition date)
AuthorsCai, W. / Sakaguchi, M. / Kleinridders, A. / Gonzalez-Del Pino, G. / Dreyfuss, J.M. / O'Neill, B.T. / Ramirez, A.K. / Pan, H. / Winnay, J.N. / Boucher, J. ...Cai, W. / Sakaguchi, M. / Kleinridders, A. / Gonzalez-Del Pino, G. / Dreyfuss, J.M. / O'Neill, B.T. / Ramirez, A.K. / Pan, H. / Winnay, J.N. / Boucher, J. / Eck, M.J. / Kahn, C.R.
External linksNat Commun / PubMed:28345670
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-5u1m:
Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / PTB domain / Insulin Receptor Substrate-1 / Phosphopeptide / Insulin Receptor

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