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-Structure paper
| Title | Structure-Enabled Discovery of a Stapled Peptide Inhibitor to Target the Oncogenic Transcriptional Repressor TLE1. |
|---|---|
| Journal, issue, pages | Chemistry, Vol. 23, Page 9577-9584, Year 2017 |
| Publish date | Jan 18, 2017 (structure data deposition date) |
Authors | McGrath, S. / Tortorici, M. / Drouin, L. / Solanki, S. / Vidler, L. / Westwood, I. / Gimeson, P. / Van Montfort, R. / Hoelder, S. |
External links | Chemistry / PubMed:28326635 |
| Methods | X-ray diffraction |
| Resolution | 2.04 Å |
| Structure data | ![]() PDB-5mwj: |
| Chemicals | ![]() ChemComp-DMS: ![]() ChemComp-EBU: ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSCRIPTION / Transducin-like; Constrained peptide inhibitor; Transcriptional corepressor |
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