+Search query
-Structure paper
Title | 6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase. |
---|---|
Journal, issue, pages | Eur J Med Chem, Vol. 128, Page 168-179, Year 2017 |
Publish date | Nov 7, 2016 (structure data deposition date) |
![]() | Tang, J. / Kirby, K.A. / Huber, A.D. / Casey, M.C. / Ji, J. / Wilson, D.J. / Sarafianos, S.G. / Wang, Z. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.705 Å |
Structure data | ![]() PDB-5tuq: |
Chemicals | ![]() ChemComp-J63: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
Source |
|
![]() | TRANSFERASE/TRANSFERASE INHIBITOR / HIV-1 / REVERSE TRANSCRIPTASE / INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex |