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TitleStructured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Journal, issue, pagesNucleic Acids Res., Vol. 45, Page 2223-2241, Year 2017
Publish dateMar 4, 2016 (structure data deposition date)
AuthorsCurrie, S.L. / Lau, D.K.W. / Doane, J.J. / Whitby, F.G. / Okon, M. / McIntosh, L.P. / Graves, B.J.
External linksNucleic Acids Res. / PubMed:28161714
MethodsX-ray diffraction
Resolution1.101 - 1.8 Å
Structure data

PDB-5ils:
Autoinhibited ETV1
Method: X-RAY DIFFRACTION / Resolution: 1.399 Å

PDB-5ilu:
Autoinhibited ETV4
Method: X-RAY DIFFRACTION / Resolution: 1.101 Å

PDB-5ilv:
Uninhibited ETV5
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / ETV1 / ETS / transcription factor / autoinhibition transcription / DNA binding / ETV4 / ETV5

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