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TitleMethyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta.
Journal, issue, pagesNucleic Acids Res., Vol. 45, Page 2503-2515, Year 2017
Publish dateAug 15, 2016 (structure data deposition date)
AuthorsHong, S. / Wang, D. / Horton, J.R. / Zhang, X. / Speck, S.H. / Blumenthal, R.M. / Cheng, X.
External linksNucleic Acids Res. / PubMed:28158710
MethodsX-ray diffraction
Resolution1.89 - 2.251 Å
Structure data

PDB-5szx:
Epstein-Barr virus Zta DNA binding domain homodimer in complex with methylated DNA
Method: X-RAY DIFFRACTION / Resolution: 2.251 Å

PDB-5t01:
Human c-Jun DNA binding domain homodimer in complex with methylated DNA
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • epstein-barr virus (Epstein-Barr virus)
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsTRANSCRIPTION REGULATOR/DNA / Zta / Zebra / BZLF-1 / AP-1 / Epstein-Barr virus / EBV / 5-methylcytosine / 5mC / DNA methylation / transcription factor / basic leucine-zipper / bZIP / TRANSCRIPTION REGULATOR-DNA complex

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