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TitleGene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page E1128-E1137, Year 2017
Publish dateOct 3, 2016 (structure data deposition date)
AuthorsChao, K.L. / Kulakova, L. / Herzberg, O.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28154144
MethodsX-ray diffraction
Resolution3.5 Å
Structure data

PDB-5tj4:
Gasdermin-B C-terminal domain containing the polymorphism residues Gly299:Pro306 fused to maltose binding protein
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-NA:
Unknown entry

Source
  • escherichia coli (E. coli)
  • homo sapiens (human)
KeywordsLIGAND BINDING PROTEIN / alpha helices / fusion protein / C-terminal domain / 1 SNP

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