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Structure paper

TitleMolecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases
Journal, issue, pagesInt J Mol Sci, Vol. 18, Year 2017
Publish dateDec 21, 2016 (structure data deposition date)
AuthorsLee, J.U. / Shin, W. / Son, J.Y. / Yoo, K.Y. / Heo, Y.S.
External linksInt J Mol Sci / PubMed:28124979
MethodsX-ray diffraction
Resolution1.952 - 2.9 Å
Structure data

PDB-5wuv:
Crystal structure of Certolizumab Fab
Method: X-RAY DIFFRACTION / Resolution: 1.952 Å

PDB-5wux:
TNFalpha-certolizumab Fab
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antibody

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