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-Structure paper
Title | Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo. |
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Journal, issue, pages | Acta Neuropathol., Vol. 133, Page 629-644, Year 2017 |
Publish date | Jul 7, 2016 (structure data deposition date) |
![]() | Pusch, S. / Krausert, S. / Fischer, V. / Balss, J. / Ott, M. / Schrimpf, D. / Capper, D. / Sahm, F. / Eisel, J. / Beck, A.C. ...Pusch, S. / Krausert, S. / Fischer, V. / Balss, J. / Ott, M. / Schrimpf, D. / Capper, D. / Sahm, F. / Eisel, J. / Beck, A.C. / Jugold, M. / Eichwald, V. / Kaulfuss, S. / Panknin, O. / Rehwinkel, H. / Zimmermann, K. / Hillig, R.C. / Guenther, J. / Toschi, L. / Neuhaus, R. / Haegebart, A. / Hess-Stumpp, H. / Bauser, M. / Wick, W. / Unterberg, A. / Herold-Mende, C. / Platten, M. / von Deimling, A. |
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Methods | X-ray diffraction |
Resolution | 2.7 Å |
Structure data | ![]() PDB-5lge: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-EDO: ![]() ChemComp-6VN: ![]() ChemComp-ACT: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / IDH1 / ALLOSTERIC INHIBITOR / NADP+ |