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TitleHigh resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate.
Journal, issue, pagesProtein Sci., Vol. 26, Page 727-736, Year 2017
Publish dateOct 7, 2014 (structure data deposition date)
AuthorsNadvi, N.A. / Salam, N.K. / Park, J. / Akladios, F.N. / Kapoor, V. / Collyer, C.A. / Gorrell, M.D. / Church, W.B.
External linksProtein Sci. / PubMed:28097769
MethodsX-ray diffraction
Resolution1.28 - 1.54 Å
Structure data

PDB-4wlh:
High resolution crystal structure of human kynurenine aminotransferase-I bound to PLP cofactor
Method: X-RAY DIFFRACTION / Resolution: 1.28 Å

PDB-4wlj:
High resolution crystal structure of human kynurenine aminotransferase-I in complex with aminooxyacetate
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-IK2:
4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Aminotransferase / Alternate conformations / Alpha beta protein / Lysine modification / Transaminase / Alpha beta protein Ligand / AOAA / Deoxy Aminopyridoxal Phosphate

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