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TitleOne-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 114, Page 998-1002, Year 2017
Publish dateNov 27, 2016 (structure data deposition date)
AuthorsCampeotto, I. / Goldenzweig, A. / Davey, J. / Barfod, L. / Marshall, J.M. / Silk, S.E. / Wright, K.E. / Draper, S.J. / Higgins, M.K. / Fleishman, S.J.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:28096331
MethodsX-ray diffraction
Resolution2.35 Å
Structure data

PDB-5mi0:
A thermally stabilised version of Plasmodium falciparum RH5
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / malaria immunogen design Rosetta PROSS

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