タイトル | Principles for designing proteins with cavities formed by curved beta sheets. |
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ジャーナル・号・ページ | Science, Vol. 355, Page 201-206, Year 2017 |
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掲載日 | 2016年7月3日 (構造データの登録日) |
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著者 | Marcos, E. / Basanta, B. / Chidyausiku, T.M. / Tang, Y. / Oberdorfer, G. / Liu, G. / Swapna, G.V. / Guan, R. / Silva, D.A. / Dou, J. ...Marcos, E. / Basanta, B. / Chidyausiku, T.M. / Tang, Y. / Oberdorfer, G. / Liu, G. / Swapna, G.V. / Guan, R. / Silva, D.A. / Dou, J. / Pereira, J.H. / Xiao, R. / Sankaran, B. / Zwart, P.H. / Montelione, G.T. / Baker, D. |
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リンク | Science / PubMed:28082595 |
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手法 | NMR (溶液) / X線回折 |
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解像度 | 1.8 - 3.101 Å |
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構造データ | PDB-5kpe: Solution NMR Structure of Denovo Beta Sheet Design Protein, Northeast Structural Genomics Consortium (NESG) Target OR664 手法: SOLUTION NMR PDB-5kph: Solution NMR Structure of Denovo Beta Sheet Design Protein, Northeast Structural Genomics Consortium (NESG) Target OR485 手法: SOLUTION NMR PDB-5l33: Crystal structure of a de novo designed protein with curved beta-sheet 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-5tph: Crystal structure of a de novo designed protein homodimer with curved beta-sheet 手法: X-RAY DIFFRACTION / 解像度: 2.47 Å PDB-5tpj: Crystal structure of a de novo designed protein with curved beta-sheet 手法: X-RAY DIFFRACTION / 解像度: 3.101 Å PDB-5trv: Crystal structure of a de novo designed protein with curved beta-sheet 手法: X-RAY DIFFRACTION / 解像度: 2.91 Å PDB-5ts4: Crystal structure of a de novo designed protein with curved beta-sheet 手法: X-RAY DIFFRACTION / 解像度: 3.005 Å PDB-5u35: Crystal structure of a de novo designed protein with curved beta-sheet 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å |
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化合物 | ChemComp-PG6: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE / ペンタグリム
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由来 | - synthetic construct (人工物)
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キーワード | DE NOVO PROTEIN / Structural Genomics / PSI-Biology / Northeast Structural Genomics Consortium / NESG / de novo NTF2 |
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