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TitleImmunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.
Journal, issue, pagesJ. Immunol., Vol. 198, Page 1047-1055, Year 2017
Publish dateJun 13, 2016 (structure data deposition date)
AuthorsWiehe, K. / Nicely, N.I. / Lockwood, B. / Kuraoka, M. / Anasti, K. / Arora, S. / Bowman, C.M. / Stolarchuk, C. / Parks, R. / Lloyd, K.E. ...Wiehe, K. / Nicely, N.I. / Lockwood, B. / Kuraoka, M. / Anasti, K. / Arora, S. / Bowman, C.M. / Stolarchuk, C. / Parks, R. / Lloyd, K.E. / Xia, S.M. / Duffy, R. / Shen, X. / Kyratsous, C.A. / Macdonald, L.E. / Murphy, A.J. / Scearce, R.M. / Moody, M.A. / Alam, S.M. / Verkoczy, L. / Tomaras, G.D. / Kelsoe, G. / Haynes, B.F.
External linksJ. Immunol. / PubMed:28011932
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-5kg9:
Crystal structure of the gp120 v2 antibody RE505-22 Fab from IGH- and IGK-humanized mouse
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HIV-1 gp120 antibody Fab

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