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-Structure paper
| Title | Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8. |
|---|---|
| Journal, issue, pages | ACS Med Chem Lett, Vol. 7, Page 1102-1106, Year 2016 |
| Publish date | Sep 21, 2016 (structure data deposition date) |
Authors | Judge, R.A. / Zhu, H. / Upadhyay, A.K. / Bodelle, P.M. / Hutchins, C.W. / Torrent, M. / Marin, V.L. / Yu, W. / Vedadi, M. / Li, F. ...Judge, R.A. / Zhu, H. / Upadhyay, A.K. / Bodelle, P.M. / Hutchins, C.W. / Torrent, M. / Marin, V.L. / Yu, W. / Vedadi, M. / Li, F. / Brown, P.J. / Pappano, W.N. / Sun, C. / Petros, A.M. |
External links | ACS Med Chem Lett / PubMed:27994746 |
| Methods | X-ray diffraction |
| Resolution | 1.3 Å |
| Structure data | ![]() PDB-5teg: |
| Chemicals | ![]() ChemComp-SAM: ![]() ChemComp-HOH: |
| Source |
|
Keywords | TRANSFERASE / Histone H4 / Norleucine |
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