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TitleCrystal Structures of Bacterial (6-4) Photolyase Mutants with Impaired DNA Repair Activity.
Journal, issue, pagesPhotochem. Photobiol., Vol. 93, Page 304-314, Year 2017
Publish dateJun 6, 2016 (structure data deposition date)
AuthorsZhang, F. / Ma, H. / Bowatte, K. / Kwiatkowski, D. / Mittmann, E. / Qasem, H. / Krau, N. / Zeng, X. / Ren, Z. / Scheerer, P. ...Zhang, F. / Ma, H. / Bowatte, K. / Kwiatkowski, D. / Mittmann, E. / Qasem, H. / Krau, N. / Zeng, X. / Ren, Z. / Scheerer, P. / Yang, X. / Lamparter, T.
External linksPhotochem. Photobiol. / PubMed:27992645
MethodsX-ray diffraction
Resolution2.149 - 2.5 Å
Structure data

PDB-5kcm:
Crystal structure of iron-sulfur cluster containing photolyase PhrB mutant I51W
Method: X-RAY DIFFRACTION / Resolution: 2.149 Å

PDB-5lfa:
Crystal structure of iron-sulfur cluster containing bacterial (6-4) photolyase PhrB - Y424F mutant with impaired DNA repair activity
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-DLZ:
1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol

Source
  • agrobacterium fabrum (strain c58 / atcc 33970) (bacteria)
KeywordsLYASE / (6-4) Photolyase / Mutant / (6-4) Photorepair / FeS-BCP / PHOTOLYASE / DNA REPAIR / IRON-SULFUR CLUSTER / FLAVOPROTEIN

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