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TitleRedox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation.
Journal, issue, pagesBiochemistry, Vol. 56, Page 179-188, Year 2017
Publish dateAug 3, 2016 (structure data deposition date)
AuthorsMahalingan, K.K. / Baskaran, S. / DePaoli-Roach, A.A. / Roach, P.J. / Hurley, T.D.
External linksBiochemistry / PubMed:27935293
MethodsX-ray diffraction
Resolution2.88 - 3.3 Å
Structure data

PDB-5suk:
G6P bound activated state of yeast glycogen synthase 2
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

PDB-5sul:
Inhibited state structure of yGsy2p
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-G6P:
6-O-phosphono-alpha-D-glucopyranose

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-U5P:
URIDINE-5'-MONOPHOSPHATE

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
KeywordsTRANSFERASE / Activated form G6P Glycogen synthase wild-type / Glycogen synthase Inhibited state / Phosphorylation

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