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| Title | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity. |
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| Journal, issue, pages | Sci Rep, Vol. 6, Page 38071-38071, Year 2016 |
| Publish date | Sep 14, 2016 (structure data deposition date) |
Authors | Lee, Y.R. / Lin, T.S. / Lai, S.J. / Liu, M.S. / Lai, M.C. / Chan, N.L. |
External links | Sci Rep / PubMed:27934872 |
| Methods | X-ray diffraction |
| Resolution | 1.776 - 2.471 Å |
| Structure data | ![]() PDB-5gwx: ![]() PDB-5h02: ![]() PDB-5hii: ![]() PDB-5hij: ![]() PDB-5hik: ![]() PDB-5hil: ![]() PDB-5him: |
| Chemicals | ![]() ChemComp-SAM: ![]() ChemComp-SAR: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-SAH: ![]() ChemComp-BET: ![]() ChemComp-DMG: |
| Source |
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Keywords | TRANSFERASE / S-adenosylmethionine-dependent methyltransferases / SAM / AdoMet-MTase / class I monomethylation / glycine / sarcosine rate-limiting enzyme / betaine biosynthesis betaine-mediated feedback inhibition / sarcosine / rate-limiting enzyme / betaine biosynthesis / betaine-mediated feedback inhibition / S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase) / class I / monomethylation of glycine and sarcosine / rate-limiting enzyme in betaine biosynthesis |
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methanohalophilus portucalensis fdf-1 (archaea)
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