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Structure paper

TitleStructural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Journal, issue, pagesBiochemistry, Vol. 55, Page 6718-6729, Year 2016
Publish dateSep 30, 2016 (structure data deposition date)
AuthorsPorter, N.J. / Christianson, N.H. / Decroos, C. / Christianson, D.W.
External linksBiochemistry / PubMed:27933794
MethodsX-ray diffraction
Resolution1.868 - 2.407 Å
Structure data

PDB-5ths:
Crystal Structure of G302A HDAC8 in complex with M344
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5tht:
Crystal Structure of G303A HDAC8 in complex with M344
Method: X-RAY DIFFRACTION / Resolution: 2.407 Å

PDB-5thu:
Crystal Structure of G304A HDAC8 in complex with M344
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-5thv:
Crystal Structure of G305A HDAC8 in complex with M344
Method: X-RAY DIFFRACTION / Resolution: 1.868 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-B3N:
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-GGG:
glycylglycylglycine

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Zinc Histone Deacetylase / Zinc Histone Deactylase

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