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TitleStructural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist.
Journal, issue, pagesStructure, Vol. 25, Page 16-26, Year 2017
Publish dateNov 17, 2015 (structure data deposition date)
AuthorsPellegrini, E. / Palencia, A. / Braun, L. / Kapp, U. / Bougdour, A. / Belrhali, H. / Bowler, M.W. / Hakimi, M.A.
External linksStructure / PubMed:27889209
MethodsX-ray diffraction
Resolution2.4 - 2.8 Å
Structure data

PDB-5eta:
Structure of MAPK14 with bound the KIM domain of the Toxoplasma protein GRA24
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5etf:
Structure of dead kinase MAPK14 with bound the KIM domain of MKK6
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • toxoplasma gondii (eukaryote)
KeywordsTRANSFERASE / MAPK14 / Gra24 / KIM domain / peptide-protein complex / MKk6

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