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Structure paper

TitleStructural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Journal, issue, pagesGenes Dev., Vol. 30, Page 2391-2403, Year 2016
Publish dateOct 10, 2016 (structure data deposition date)
AuthorsJin, W. / Wang, Y. / Liu, C.P. / Yang, N. / Jin, M. / Cong, Y. / Wang, M. / Xu, R.M.
External linksGenes Dev. / PubMed:27881601
MethodsX-ray diffraction
Resolution1.9 - 2.492 Å
Structure data

PDB-5h1j:
Crystal structure of WD40 repeat domains of Gemin5
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5h1k:
Crystal structure of WD40 repeat domains of Gemin5 in complex with 13-nt U4 snRNA fragment
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5h1l:
Crystal structure of WD40 repeat domains of Gemin5 in complex with 7-nt U4 snRNA fragment
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5h1m:
Crystal structure of WD40 repeat domains of Gemin5 in complex with M7G
Method: X-RAY DIFFRACTION / Resolution: 2.492 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-M7G:
7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE

Source
  • homo sapiens (human)
KeywordsSPLICING / WD repeat / Gemin5 / SMN / SPLICING/RNA / RNA binding / U4 snRNA / SPLICING-RNA complex

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