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Structure paper

TitleStructure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
Journal, issue, pagesCell, Vol. 167, Page 1028-1040.e15, Year 2016
Publish dateSep 2, 2016 (structure data deposition date)
AuthorsPetrovic, A. / Keller, J. / Liu, Y. / Overlack, K. / John, J. / Dimitrova, Y.N. / Jenni, S. / van Gerwen, S. / Stege, P. / Wohlgemuth, S. ...Petrovic, A. / Keller, J. / Liu, Y. / Overlack, K. / John, J. / Dimitrova, Y.N. / Jenni, S. / van Gerwen, S. / Stege, P. / Wohlgemuth, S. / Rombaut, P. / Herzog, F. / Harrison, S.C. / Vetter, I.R. / Musacchio, A.
External linksCell / PubMed:27881301
MethodsX-ray diffraction
Resolution2.002 - 3.502 Å
Structure data

PDB-5lsi:
CRYSTAL STRUCTURE OF THE KINETOCHORE MIS12 COMPLEX HEAD2 SUBDOMAIN CONTAINING DSN1 AND NSL1 FRAGMENTS
Method: X-RAY DIFFRACTION / Resolution: 2.002 Å

PDB-5lsj:
CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

PDB-5lsk:
CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 3.502 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / ALPHA-HELICAL

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