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Structure paper

TitleDistinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 113, Page E7399-E7408, Year 2016
Publish dateAug 31, 2016 (structure data deposition date)
AuthorsVaisey, G. / Miller, A.N. / Long, S.B.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:27821745
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-5t5n:
Calcium-activated chloride channel bestrophin-1 (BEST1), triple mutant: I76A, F80A, F84A; in complex with an Fab antibody fragment, chloride, and calcium
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
  • mus musculus (house mouse)
KeywordsMEMBRANE PROTEIN / ion channel / anion / chloride / calcium-activated / eukaryotic membrane protein / CaCC

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