Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Journal, issue, pages	Nat Commun, Vol. 7, Page 13354-13354, Year 2016
Publish date	Jun 16, 2016 (structure data deposition date)
Authors	Lee, J.Y. / Lee, H.T. / Shin, W. / Chae, J. / Choi, J. / Kim, S.H. / Lim, H. / Won Heo, T. / Park, K.Y. / Lee, Y.J. ...Lee, J.Y. / Lee, H.T. / Shin, W. / Chae, J. / Choi, J. / Kim, S.H. / Lim, H. / Won Heo, T. / Park, K.Y. / Lee, Y.J. / Ryu, S.E. / Son, J.Y. / Lee, J.U. / Heo, Y.S.
External links	Nat Commun / PubMed:27796306
Methods	X-ray diffraction
Resolution	1.9 - 3.3 Å
Structure data	PDB-5ggq: Crystal structure of Nivolumab Fab fragment Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-5ggr: PD-1 in complex with nivolumab Fab Method: X-RAY DIFFRACTION / Resolution: 3.3 Å PDB-5ggs: PD-1 in complex with pembrolizumab Fab Method: X-RAY DIFFRACTION / Resolution: 1.997 Å PDB-5ggt: PD-L1 in complex with BMS-936559 Fab Method: X-RAY DIFFRACTION / Resolution: 2.8 Å PDB-5ggu: Crystal structure of tremelimumab Fab Method: X-RAY DIFFRACTION / Resolution: 2.292 Å PDB-5ggv: CTLA-4 in complex with tremelimumab Fab Method: X-RAY DIFFRACTION / Resolution: 1.998 Å
Chemicals	ChemComp-HOH: WATER
Source	homo sapiens (human)
Keywords	IMMUNE SYSTEM / therapeutic antibody / antibody