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TitleInsights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.
Journal, issue, pagesElife, Vol. 5, Year 2016
Publish dateJul 29, 2016 (structure data deposition date)
AuthorsSchulze-Gahmen, U. / Echeverria, I. / Stjepanovic, G. / Bai, Y. / Lu, H. / Schneidman-Duhovny, D. / Doudna, J.A. / Zhou, Q. / Sali, A. / Hurley, J.H.
External linksElife / PubMed:27731797
MethodsX-ray diffraction
Resolution5.9 Å
Structure data

PDB-5l1z:
TAR complex with HIV-1 Tat-AFF4-P-TEFb
Method: X-RAY DIFFRACTION / Resolution: 5.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
  • human immunodeficiency virus type 1 group m subtype b (isolate bh10)
  • human immunodeficiency virus 1
Keywordstranscription/RNA / HIV-1 TAR / protein-RNA complex / transcription / protein kinase / transcription-RNA complex

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