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TitleMechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization.
Journal, issue, pagesCell Death Differ., Vol. 23, Page 1930-1940, Year 2016
Publish dateJan 19, 2016 (structure data deposition date)
AuthorsGebel, J. / Luh, L.M. / Coutandin, D. / Osterburg, C. / Lohr, F. / Schafer, B. / Frombach, A.S. / Sumyk, M. / Buchner, L. / Krojer, T. ...Gebel, J. / Luh, L.M. / Coutandin, D. / Osterburg, C. / Lohr, F. / Schafer, B. / Frombach, A.S. / Sumyk, M. / Buchner, L. / Krojer, T. / Salah, E. / Mathea, S. / Guntert, P. / Knapp, S. / Dotsch, V.
External linksCell Death Differ. / PubMed:27716744
MethodsNMR (solution) / X-ray diffraction
Resolution1.36007789334 Å
Structure data

PDB-2nb1:
P63/p73 hetero-tetramerisation domain
Method: SOLUTION NMR

PDB-5hoc:
p73 homo-tetramerization domain mutant II
Method: X-RAY DIFFRACTION / Resolution: 1.36007789334 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / p63 / p73 / tetramerization domain / hetero tetramer / transcription factor / homo-tetramerization mutant / hetero-tetramerization

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