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-Structure paper
Title | NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine. |
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Journal, issue, pages | Cancer Res., Vol. 76, Page 5501-5511, Year 2016 |
Publish date | Aug 12, 2016 (structure data deposition date) |
Authors | Valerie, N.C. / Hagenkort, A. / Page, B.D. / Masuyer, G. / Rehling, D. / Carter, M. / Bevc, L. / Herr, P. / Homan, E. / Sheppard, N.G. ...Valerie, N.C. / Hagenkort, A. / Page, B.D. / Masuyer, G. / Rehling, D. / Carter, M. / Bevc, L. / Herr, P. / Homan, E. / Sheppard, N.G. / Stenmark, P. / Jemth, A.S. / Helleday, T. |
External links | Cancer Res. / PubMed:27530327 |
Methods | X-ray diffraction |
Resolution | 1.7 Å |
Structure data | PDB-5lpg: |
Chemicals | ChemComp-MG: ChemComp-71V: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / MTH2 / DNA repair enzyme / Cancer |