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Structure paper

TitleStructural basis of laminin binding to the LARGE glycans on dystroglycan.
Journal, issue, pagesNat. Chem. Biol., Vol. 12, Page 810-814, Year 2016
Publish dateMar 3, 2016 (structure data deposition date)
AuthorsBriggs, D.C. / Yoshida-Moriguchi, T. / Zheng, T. / Venzke, D. / Anderson, M.E. / Strazzulli, A. / Moracci, M. / Yu, L. / Hohenester, E. / Campbell, K.P.
External linksNat. Chem. Biol. / PubMed:27526028
MethodsX-ray diffraction
Resolution1.27 - 2 Å
Structure data

PDB-5ik4:
Laminin A2LG45 C-form, Apo.
Method: X-RAY DIFFRACTION / Resolution: 1.27 Å

PDB-5ik5:
Laminin A2LG45 C-form, G6/7 bound.
Method: X-RAY DIFFRACTION / Resolution: 1.39 Å

PDB-5ik7:
Laminin A2LG45 I-form, Apo.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5ik8:
Laminin A2LG45 I-form, G6/7 bound.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-A2G:
2-acetamido-2-deoxy-alpha-D-galactopyranose

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-4MU:
7-hydroxy-4-methyl-2H-chromen-2-one

ChemComp-FLC:
CITRATE ANION

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • mus musculus (house mouse)
KeywordsSTRUCTURAL PROTEIN / Extracellular Matrix / Ligand binding / LG domain

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