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Structure paper

TitleConformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling.
Journal, issue, pagesStructure, Vol. 24, Page 1271-1281, Year 2016
Publish dateNov 13, 2013 (structure data deposition date)
AuthorsBroughton, S.E. / Hercus, T.R. / Nero, T.L. / Dottore, M. / McClure, B.J. / Dhagat, U. / Taing, H. / Gorman, M.A. / King-Scott, J. / Lopez, A.F. / Parker, M.W.
External linksStructure / PubMed:27396825
MethodsX-ray diffraction
Resolution2.68 - 3.301 Å
Structure data

PDB-4nkq:
Structure of a Cytokine Receptor Complex
Method: X-RAY DIFFRACTION / Resolution: 3.301 Å

PDB-4rs1:
Crystal structure of receptor-cytokine complex
Method: X-RAY DIFFRACTION / Resolution: 2.68 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE/CYTOKINE RECEPTOR / GM-CSF / receptor complex / dodecamer / Disease mutation / Glycoprotein / Membrane / Phosphoprotein / Transmembrane / Cytokine / Growth factor / Secreted / CYTOKINE-CYTOKINE RECEPTOR complex / CYTOKINE RECEPTOR/CYTOKINE / RECEPTOR / CYTOKINE RECEPTOR-CYTOKINE COMPLEX

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